This will be a low karma / slow advancement campaign.
You can expect to earn between 3 and 10 karma per mission, with the average being closer to 5.
Each "game week" you can improve one skill or attribute. Some advancements may take even longer, such as initiating or creating a familiar.
Gear takes time to obtain. If you want anything with a high availability rating you will most likely need to make arrangements between sessions to get it.